Table 1.
Characteristic | Total | Control group | CIK group | P |
---|---|---|---|---|
No. of patients | 122 | 62 | 60 | |
Sex | 0.536 | |||
Male | 78 | 38 | 40 | |
Female | 44 | 24 | 20 | |
Age (years) | 0.606 | |||
≥ 60 | 34 | 16 | 18 | |
< 60 | 88 | 46 | 42 | |
Primary tumor | 0.498 | |||
Rectum | 43 | 24 | 19 | |
Left-sided colon | 46 | 24 | 22 | |
Right-sided colon | 33 | 14 | 19 | |
Histology | 1.000a | |||
Well differentiated | 9 | 5 | 4 | |
Moderate differentiated | 84 | 42 | 42 | |
Poorly differentiated | 29 | 15 | 14 | |
T stage | 0.597a | |||
T1 + T2 | 8 | 3 | 5 | |
T3 | 65 | 32 | 33 | |
T4 | 49 | 27 | 22 | |
N stage | 0.186 | |||
N0 | 33 | 20 | 13 | |
N1 | 65 | 28 | 37 | |
N2 | 24 | 14 | 10 | |
TNM stageb | 0.021a | |||
II | 32 | 21 | 11 | |
III | 86 | 41 | 45 | |
IV | 4 | 0 | 4 | |
Tumor size (cm) | 0.161 | |||
< 4 | 34 | 17 | 17 | |
≥ 4 | 38 | 15 | 23 | |
Missing data | 50 | 30 | 20 | |
Neural invasion | 0.520 | |||
Absent | 91 | 48 | 43 | |
Present | 15 | 8 | 7 | |
Missing data | 16 | 6 | 10 | |
Venous invasion | 0.452 | |||
Absent | 78 | 40 | 38 | |
Present | 28 | 16 | 12 | |
Missing data | 16 | 6 | 10 | |
MMR status | 0.519a | |||
dMMR | 3 | 1 | 2 | |
pMMR | 34 | 15 | 19 | |
Missing data | 85 | 46 | 39 | |
Chemotherapy regimen | 0.371a | |||
FOLFOX | 31 | 19 | 12 | |
CAPOX | 81 | 39 | 42 | |
Capecitabine | 10 | 4 | 6 | |
Duration of chemotherapy | 0.252 | |||
> 20 weeks | 73 | 34 | 39 | |
< 20 weeks | 49 | 28 | 21 | |
Adjuvant radiotherapy | 0.504 | |||
Yes | 12 | 5 | 7 | |
No | 110 | 57 | 53 | |
Neoadjuvant chemotherapy | 0.145 | |||
Yes | 18 | 12 | 6 | |
No | 104 | 50 | 54 | |
Neoadjuvant radiotherapy | 0.373 | |||
Yes | 11 | 7 | 4 | |
No | 111 | 55 | 56 |
CIK, cytokine-induced killer cell. CAPOX, Capecitabine + Oxaliplatin. FOLFOX, Oxaliplatin + 5-fluorouracil. MMR, mismatch repair; dMMR, MMR-defcient; pMMR, MMR-profcient.
a, Fisher’s exact test. b, According to the 8th edition of the American Joint Committee on Cancer staging system.