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. 2020 Apr 1;21(6):2533–2543. doi: 10.3892/mmr.2020.11047

Table II.

KEGG pathway enrichment analysis of green module and brown modules.

Category Term Description Count % FDR
Green module
  KEGG hsa04060 Cytokine-cytokine receptor interaction 40 5.128205 3.32×10−10
  KEGG hsa04974 Protein digestion and absorption 22 2.820513 7.29×10−8
  KEGG hsa04512 ECM-receptor interaction 18 2.307692 1.27×10−4
  KEGG hsa05146 Amoebiasis 19 2.435897 4.96×10−4
  KEGG hsa05323 Rheumatoid arthritis 16 2.051282 4.50×10−3
  KEGG hsa04151 PI3K-Akt signaling pathway 33 4.230769 2.73×10−2
  KEGG hsa04062 Chemokine signaling pathway 22 2.820513 4.61×10−2
  KEGG hsa04668 TNF signaling pathway 14 1.794872 7.10×10−1
  KEGG hsa04310 Wnt signaling pathway 16 2.05128 9.10×10−1
Brown module
  KEGG hsa00830 Retinol metabolism 24 1.656315 1.39×10−8
  KEGG hsa05204 Chemical carcinogenesis 23 1.587302 1.30×10−5
  KEGG hsa00982 Drug metabolism-cytochrome P450 20 1.380262 1.02×10−4
  KEGG hsa00910 Nitrogen metabolism 9 0.621118 8.46×10−3
  KEGG hsa00980 Metabolism of xenobiotics by cytochrome P450 18 1.242236 9.57×10−3
  KEGG hsa00140 Steroid hormone biosynthesis 15 1.035197 3.38×10−2
  KEGG hsa04978 Mineral absorption 13 0.89717 3.44×10−2

FDR, false discovery ratio; KEGG, Kyoto Encyclopedia of Genes and Genomes; ECM, extracellular matrix; TNF, tumor necrosis factor.