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. 2020 Mar 30;21(6):2357–2366. doi: 10.3892/mmr.2020.11044

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Copyright: © Xu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Suppression of CD44 decreases the expression of chondrocyte-associated genes. Relative expression levels of (A) CD44, (B) Sox9, (C) Co2α1 and (D) Acan in P3 hAMSCs were detected by reverse transcription-quantitative polymerase chain reaction on day 7 after treatment with A3D8. Data were presented as mean ± standard errors of the mean (n=3). *P<0.05 and **P<0.01. CD, cluster of differentiation; hAMSCs, human amniotic mesenchymal stem cells; Sox9, SRY-box transcription factor 9; Col2a1, collagen type II α 1 chain; Acan, aggrecan; NC, negative control group; PG, positive drug group.