Table 1.
Factors associated with candidemia in hemodialysis patients.
| Variable | Cases n = 77 (%) | Controls n = 154 (%) | P-value Odds Ratio |
|---|---|---|---|
| Implantable vascular catheter* | 57 (74) | 72 (46.8) | <0.0001 3.24 (1.78 –5.91) |
| TPN | 15 (19.5) | 2 (1.3) | <0.0001 18.38 (4.08 –82.79) |
| Neutropenia | 4 (5.2) | 0 | 0.01 † |
| Surgery | 38 (49.4) | 73 (47.4) | 0.88 1.08 (0.62 –1.87) |
| Corticosteroids | 10 (13) | 17 (11) | 0.82 1.20 (0.52 –2.77) |
| Diabetes mellitus | 45 (58.4) | 99 (64.3) | 0.74 0.78 (0.43 –1.42) |
| Cirrhosis | 3 (3.9) | 6 (3.9) | 1.0 1 (0.19 –4.67) |
| Cancer | 8 (10.4) | 8(5.2) | 0.11 2.12 (0.76 –5.87) |
| Antibiotic use | 64 (83.1) | 106 (68.8) | 0.03 2.23 (1.12 –4.43) |
| Mortality | 40 (51.9) | 12 (7.8) | <0.0001 12.79 (5.78 –28.8) |
| Multivariate analysis | |||
| Implantable catheter | 57 (74) | 72(46.8) | 0.0001 3.25 (1.71 –6.19) |
| TPN | 15 (19.5) | 2 (1.3) | <0.0001 18.39 (3.85 –120.13) |
| Antibiotic use | 64 (83.1) | 106 (68.8) | 0.13 0.67 (0.39 –1.17) |
Includes tunneled and non-tunneled catheters
odds ratio was not determined as no patients in the control group had neutropenia.