Table 2.

Recommendations for Screening of High Risk Individuals

Expert Group	Patients	Age	Screening Intervention	Reference
The International Cancer of the Pancreas Screening (CAPS) Consortium	-FDRs of patients with PC from a familial PC kindred with at least two affected FDRs -Peutz-Jeghers syndrome -p16/CDKN2A mutation -BRCA2 and hereditary non-polyposis colorectal cancer (HNPCC) mutation carriers with ≥ 1 affected FDR	No Consensus	EUS or MRI, No consensus on screening interval but 12 months is currently suggested	[5]
American College of Gastroenterology	-FDRs of patients with PC from a familial PC kindred with at least two affected FDRs -Peutz-Jeghers syndrome -Patients with a mutation in BRCA1/2, ATM, PALB2, or Lynch syndrome genes and a FDR or SDR with PC	Age 50 or 10 years before the earliest age of pancreas cancer	Annual EUS and/or MRI	[47]

Abbreviations: PC, Pancreas Cancer; FDR, First Degree Relative; SDR, Second degree relative; EUS, Endoscopic Ultrasound; MRI, Magnetic Resonance Imaging.