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. 2020 Apr 23;15:2873–2884. doi: 10.2147/IJN.S242787

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© 2020 Liu et al.

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Intracellular distribution of NPs. (A) Prussian blue staining of MC38 cells after incubation with NPs for 4 h. Scale bar=20μm. (B) (a) Flow cytometry analysis of the MC38 cells treated with free DOX, DOX-SPIO and DOX-SPIO@MSCs for 30 and 240 min. (b) The DOX mean fluorescence intensity (MFI) of the MC38 cells. (C) Fluorescent staining images of the MC38 cells treated with different drugs for 240 min. Scale bar=40μm.