Table 2.
Basal concentrations of extracellular dopamine and glutamic acid in the dialysate from the Acb shell of WT, HET and DAT KO rats.
| Parameter | Line | One-way ANOVA | |||
|---|---|---|---|---|---|
| WT (N = 8) | HET (N = 10) | DAT KO (N = 8) | F(2,23) | p | |
| Dopamine (nM) | 1.98 ± 0.18 | 5.27 ± 0.40 | 18.72 ± 3.64****### | 19.38 | >0.0001 |
| Glutamic Acid (μM) | 0.80 ± 0.12 | 0.71 ± 0.07 | 0.59 ± 0.06 | 1.39 | 0.2692 |
****P < 0.0001 vs. WT. ###P < 0.001 DAT KO vs. HET. One-way ANOVAs followed by Tukey’s pairwise comparisons. Values are means ± SEM of the means of the last four dialysate aliquots of 8/10 rats/group collected before the introduction of the female rat in the mating cage.