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. 2020 Apr 23;15:2789–2808. doi: 10.2147/IJN.S243155

Table 1.

Dendrimer Shell Modification(s) and Conjugation(s) for the Respective Dendrimer Generation Investigated, Ordered from G1-G7

Investigation Dendrimer Construct(s) Dendrimer Shell Conjugation/Modification(s)
Choi et al (2017)66 G1 PEG-PLGA
Pedro-Hernandez et al (2017)72 G1 and G2 Ethyphenyl and dodecyl alkyl
Stenstrӧm et al (2018)65 G1-G4 [2,2-bis(methylol)propionic acid core] Ammonium trifluoroacetate end groups
Janiszewska et al (2016)73 G2 Poly-L-lysine
Uram et al (2018, 2019)78,79 G3 Biotin
Uram et al (2017)63 G3 Biotin
McNerny et al (2009)57 G3 c(RGDyK) and biotin
Kaneshiro et al (2009)58 G3 Poly-lysine
Singh et al (2019)59 G3.5-G4 Ammine
Carboxyl
Bae et al (2019)60 G4 Phenylalanine, histidine, and arginine
Munro et al (2019)61 G4 Hydroxyl:amine (90:10)
Wu et al (2018)77 G4 PEG
Liu et al (2018)87 G4 TAT
PEG
Bae et al (2017)71 G4 Histidine and Arginine
Histidine and Lysine
Bae et al (2016)70 G4 Histidine and Arginine
Histidine and Lysine
Zhang et al (2015)74 G4 PEG
Hydroxyl
Yang et al (2014)88 G4 Gd-NGO
Bai et al (2013)89 G4 Arginine
Qiu et al (2018)62 G5 β-CD moiety
Au
Lesniak et al (2016)90 G5 N/A
Jiang et al (2016)75 G5 PEG
Zhao et al (2015)76 G5 PEG
Yan et al (2011)54 G5 PEG
Ren et al (2010)55 G5 N/A
Ofek et al (2010)56 G5 Polyglycerol
Perez et al (2011)34 G7 N/A