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. 2020 Apr 9;37(8):1021–1028. doi: 10.1089/neu.2019.6661

Table 3.

Mental Health, Quality of Life, and Lifestyle Factors in Former Professional American-Style Football Players Reporting Daily Problems in Cognitive Functiona Compared with Those Who Do Not Report Daily Cognitive Problems

Characteristic Daily cognitive problems (n = 1502) No daily cognitive problems (n = 2256) OR [95% CI]
Mental healthb      
Depression      
 Yes 259 (18.0) 73 (3.3) 6.42
 No 1183 (82.0) 2140 (96.7) [4.90–8.40]
Anxiety      
 Yes 276 (19.1) 94 (4.3) 5.29
 No 1171 (80.9) 2109 (95.7) [4.14–6.75]
Memory loss      
 Yes 137 (9.5) 12 (0.5) 19.14
 No 1300 (90.5) 2179 (99.5) [10.56–34.66]
ADD/ADHD      
 Yes 118 (8.1) 37 (1.7) 5.16
 No 1334 (91.9) 2157 (98.3) [3.54–7.51]
Quality of life      
 General quality of life      
  Poor/fair 553 (37.5) 147 (6.6) 8.48
  Good to excellent 923 (62.5) 2080 (93.4) [6.96–10.33]
 Mental health      
  Poor/fair 935 (62.7) 246 (11.0) 13.63
  Good to excellent 557 (37.3) 1997 (89.0) [11.51–16.14]
 Satisfaction with social activities and relationships      
  Poor/fair 725 (48.6) 244 (10.9) 7.73
  Good to excellent 767 (51.4) 1995 (89.1) [6.54–9.14]
 Emotional problems      
  Often/always 717 (47.9) 163 (7.3) 11.77
  Never to sometimes 779 (52.1) 2085 (92.7) [9.75–14.22]
Lifestyle      
 Frequent drinkingc      
  Yes 326 (22.0) 447 (20.0) 1.13
  No 1154 (78.0) 1787 (80.0) [0.96–1.33]
 Current smoking      
  Yes 66 (4.4) 52 (2.3) 1.96
  No 1419 (95.6) 2189 (97.7) [1.35–2.83]
 Low level of exercised      
  Yes 416 (27.7) 310 (13.8) 2.41
  No 1084 (72.3) 1943 (86.2) [2.04–2.84]

Data are presented as n (%).

a

Assessed with 11 questions from the Quality of Life in Neurological Disorders (Neuro-QOL) Item Bank v1.0 for Applied Cognition – General Concerns. Twenty-one out of 3779 participants provided valid responses for <8 out of 11 Neuro-QOL items and were not included in the analysis. Total values of <3758 for an outcome indicate missing responses. bBased on self-report of currently taking medication for the treatment of that disorder. cDefined as ≥15 alcoholic beverages (i.e., 12 oz. of beer, 5 oz. of wine, or one shot [2 cL] of alcohol, such as gin, rum, or vodka) per week based on the Centers for Disease Control and Prevention's classification for heavy drinking.26

d

Defined as <1 h/week of walking, jogging, running, other aerobic (e.g., bicycling, stationary/elliptical machine/other), low-intensity exercise (e.g., yoga, Pilates, stretching), and/or weight training.

ADD, attention deficit disorder; ADHD, attention deficit/hyperactivity disorder; CI, confidence interval; OR, odds ratio.