Average accuracy and RMSD of sensitivity analysis on phylogeny-free (top) and phylogeny-based methods (bottom) as functions of noise level and number of tumor samples. The top row shows the results for phylogeny-free method, and the bottom row shows the results for phylogeny-based method. The left column shows the average accuracy of inferred copy numbers, the center column average RMSD between inferred and true copy numbers, and the right column average RMSD between the inferred and true mixture fractions. Bar plots show performance at different noise levels 0.0, 0.2, and 0.4. The X-axis shows the number of tumor samples, and the Y-axis the average accuracy or RMSD.