Table 3.
Distribution of respiratory pathogens detected by multiplex PCR from nasopharyngeal aspirate (NPA) and/or lower respiratory tract samples (LRT).
| No. detected (%) |
Sensitivitya (No. of positive results/ total No. detected, %) |
||||||
|---|---|---|---|---|---|---|---|
| Total (NPA and/or LRT) |
Both on NPA and LRT | Only on NPA | Only on LRT | NPA | LRT | p valueb | |
| Influenza virus (A, B, and A H1N1 pdm09) | 29 | 27 (93) | 0 | 2 | 93 | 100 | 0.49 |
| Rhino/enterovirus | 10 | 8 (80) | 1 | 1 | 90 | 90 | NA |
| Corona virus (HKU1, OC43, NL63, and 229E) | 8 | 5 (62.5) | 0 | 3 | 62.5 | 100 | 0.2 |
| Parainfluenza virus 1 and 3 | 6 | 3 (50) | 3 | 0 | 100 | 50 | 0.181 |
| Respiratory syncytial virus A and B | 5 | 5 (100) | 0 | 0 | 100 | 100 | NA |
| Human metapneumovirus | 5 | 5 (100) | 0 | 0 | 100 | 100 | NA |
| Bocavirus type 1 | 5 | 1 (20) | 3 | 1 | 80 | 40 | 0.523 |
| Adenovirus | 3 | 0 (NA) | 1 | 2 | NA | NA | NA |
| Legionella pneumophila | 6 | 1 (17) | 0 | 5 | 16.5 | 100 | 0.015 |
| Mycoplasma pneumoniae | 1 | 0 (NA) | 1 | 0 | NA | NA | NA |
| Total | 78 | 55 (70.5) |
9 (11.5) |
14 (18) |
82 | 88.5 | 0.366 |
NA: Not applicable.
a
Sensitivity was calculated based on the presence of a respiratory pathogen in either NPAs or LRT samples over the total number of pathogens identified in both sample types.
b
Fisher’s exact test or Chi-square test.