Table II.
Patients' characteristics at study enrollment
| Characteristic | Patients who completed symptom diaries (n = 69) | Patients who did not complete symptom diaries (n = 65) | P value |
|---|---|---|---|
| Age (y), median (IQR) | 59.36 (46.74-68.22) | 45.02 (36.33-53.79) | <.001 |
| Female patients, n (%) | 41 (59) | 36 (55) | .73 |
| IgG trough level∗ (g/L), median (IQR) | 9.0 (8.0-10.0) | 9.0 (7.8-10.6) | .99 |
| Prophylactic antibiotic, n (%) | 45 (65) | ||
| Amoxicillin | 7 (10) | ||
| Azithromycin | 22 (32) | ||
| Ciprofloxacin | 3 (4) | ||
| Clarithromycin | 3 (4) | ||
| Co-amoxiclav | 2 (3) | ||
| Cotrimoxazole | 2 (3) | ||
| Doxycycline | 4 (6) | ||
| Lymecycline | 1 (1) | ||
| Penicillin | 1 (1) | ||
| Smoking status, n (%) | |||
| Current smoker | 6 (9) | 4 (6) | .92 |
| Past smoker | 15 (22) | 15 (23) | |
| Never a smoker | 48 (70) | 46 (71) | |
| Bronchiectasis on CT, n (%) | 37 (57.81) | 29 (49.15) | .22 |
| BSI score†, median (IQR) | 3.5 (2-6) | 2 (1-4) | .01 |
| FEV1 (L), median (IQR) | 2.24 (1.80-3.23) | 2.63 (2.12-3.36) | .11 |
| FEV1 predicted‡ (%), median (IQR) | 93.2 (73.3-102.9) | 93.5 (74.6-105.4) | .95 |
| SGRQ§ total score, median (IQR) | 24.47 (8.41-45.54) | ||
| SGRQ symptoms score, median (IQR) | 39.28 (23.76-58.56) | ||
| SGRQ activity score, median (IQR) | 29.31 (5.96-59.46) | ||
| SGRQ impact score, median (IQR) | 14.90 (1.98-29.90) |
CT, X-ray computed tomography.
Note. P values were calculated using the Wilcoxon rank sum test for continuous variables and the Fisher exact test for categorical variables.
Serum IgG level measured immediately before the next immunoglobulin replacement is administered.
Bronchiectasis severity index, ranging from 0 (best) to 25 (worst), is a validated multicomponent score in bronchiectasis that predicts the future risk of exacerbations, hospitalizations, and mortality.
FEV1 predicted is the proportion of actual FEV1 vs predicted FEV1 in accordance with the European Respiratory Society guidelines of 1993.
The SGRQ is a validated measure of respiratory health status scored between 0 (best) and 100 (worst) quality of life.