Figure 3.

Model of perinuclear structure. Early in the infection process, the incoming viral RNA is translated and the viral gene products contribute to the formation of the perinuclear globular structure. Following replication events (i.e., negative and positive-sense RNA transcription) that take place within this globular structure, viral egress is initiated by vesicle budding. Vesicles then traffic along the ER/microfilaments towards the plasma membrane and plasmodesmata for ultimate delivery of the virus into neighboring cells.

Reproduced from [41^••] with permission of the American Society for Microbiology.