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Enzyme activity and N3 inhibition data for MHV-A59 Mpro.
| Virus Mpro | Km (μM) | kcat (S−1) | Inhibitor N3 |
|
|---|---|---|---|---|
| Ki (μM) | k3 (10−3٠S−1) | |||
| MHV-A59-L284F | 57.31 ± 6.41 | 0.76 ± 0.06 | 0.26 ± 0.04 | 57.02 ± 5.11 |
| MHV-A59-L284F-ΔS46A47 | 40.23 ± 5.33 | 0.22 ± 0.02 | 0.23 ± 0.04 | 76.84 ± 8.88 |
