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. 2020 Apr 27;15(4):e0231078. doi: 10.1371/journal.pone.0231078

Table 3. Associations of rosacea with skin care behaviors and subgroup analyses.

Total patients Neutral skin Dry skin Oily skin Mixed skin
OR (95%CI) P (adjusted Pa) OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P
Skin type
    Neutral 1
    Dry 6.751 (4.606–9.895) <0.001 (<0.001) N/A N/A N/A N/A
    Oily 6.109 (4.153–8.986) <0.001 (<0.001) N/A N/A N/A N/A
    Mixed 6.624 (4.629–9.480) <0.001 (<0.001) N/A N/A N/A N/A
Skin care frequency
    Hardly 1 1 1 1
    1 / day 0.982 (0.567–1.7) 0.947 (0.947) N/Ab 23.417 (1.664–329.48) 0.019 0.548 (0.191–1.573) 0.264 1.360 (0.518–3.572) 0.533
    2 / day 1.841 (1.052–3.221) 0.032 (0.043) N/Ab 27.225 (1.915–387.025) 0.015 1.825 (0.63–5.289) 0.268 2.303 (0.839–6.319) 0.105
    ≥ 3 / day 0.492 (0.202–1.194) 0.117 (0.138) N/Ab 32.103 (1.571–656) 0.024 0.780 (0.128–4.737) 0.787 0.234 (0.045–1.218) 0.084
Function of skin care products
    Moisturizing 0.602 (0.386–0.938) 0.025 (0.035) N/Ab 0.019 (0.002–0.237) 0.002 0.631 (0.284–1.399) 0.257 0.674 (0.322–1.41) 0.295
    Anti-aging 0.607 (0.396–0.929) 0.022 (0.032) 0.817 (0.206–3.237) 0.773 0.803 (0.265–2.44) 0.699 0.325 (0.092–1.142) 0.080 0.569 (0.292–1.109) 0.098
    Anti-allergy 1.902 (1.297–2.788) 0.001 (0.002) 1.359 (0.338–5.458) 0.666 1.479 (0.477–4.585) 0.498 1.880 (0.801–4.41) 0.147 2.537 (1.417–4.534) 0.002
Ways of buying products
    Salon 2.334 (1.435–3.796) 0.001 (0.002) 6.250 (1.589–24.585) 0.009 4.437 (1.497–13.151) 0.007 0.825 (0.168–4.056) 0.813 2.222 (1.016–4.86) 0.046
    Online 0.551 (0.391–0.777) 0.001 (0.002) 0.278 (0.074–1.043) 0.058 0.231 (0.074–0.724) 0.012 0.408 (0.179–0.927) 0.032 0.821 (0.5–1.347) 0.435
    Direct selling 0.516 (0.339–0.785) 0.002 (0.003) 0.457 (0.118–1.771) 0.257 0.636 (0.239–1.692) 0.365 0.237 (0.083–0.677) 0.007 0.621 (0.302–1.274) 0.195
Cleansing frequency
    Hardly 1 1 1 1 1
    1~3 / week 0.647 (0.429–0.975) 0.038 (0.049) 0.240 (0.058–0.996) .049 0.576 (0.204–1.626) 0.298 0.361 (0.148–0.882) 0.025 0.887 (0.445–1.768) 0.733
    1 / day 1.117 (0.783–1.592) 0.542 (0.556) 1.358 (0.443–4.16) .592 1.684 (0.721–3.932) 0.228 0.706 (0.328–1.52) 0.374 1.023 (0.553–1.895) 0.942
    ≥ 2 / day 2.131 (1.394–3.256) <0.001 (<0.001) 2.472 (0.682–8.956) .168 3.103 (1.110–8.677) 0.031 1.493 (0.617–3.614) 0.374 2.308 (1.102–4.835) 0.027
Type of cleansers
    Foam 1.450 (1.115–1.886) 0.006 (0.01) 3.752 (1.54–9.142) 0.004 0.918 (0.457–1.84) 0.809 2.255 (1.221–4.164) 0.009 1.12 (0.741–1.692) 0.59
Facial mask frequency
    Hardly 1 1 1 1 1
    1 / week 0.874 (0.62–1.231) 0.440 (0.477) 1.166 (0.4–3.396) 0.779 0.977 (0.4–2.388) 0.959 1.153 (0.528–2.514) 0.721 0.675 (0.387–1.176) 0.165
    2~3 / week 1.460 (1.016–2.096) 0.041 (0.051) 0.494 (0.131–1.86) 0.297 1.733 (0.699–4.298) 0.235 2.267 (0.944–5.447) 0.067 1.504 (0.865–2.615) 0.148
    4~5/ week 3.069 (1.636–5.757) <0.001 (<0.001) 4.161 (0.528–32.777) 0.176 23.001 (1.338–395.484) 0.031 10.250 (2.567–40.926) 0.001 1.644 (0.648–4.17) 0.295
    ≥ 6/week 2.560 (1.561–4.198) <0.001 (<0.001) 2.726 (0.458–16.231) 0.271 6.826 (1.774–26.263) 0.005 2.572 (0.804–8.223) 0.111 1.968 (0.93–4.166) 0.077
Beauty salon frequency
    Hardly 1 1 1 1 1
    ≤ 2 / month 0.779 (0.532–1.142) 0.201 (0.231) 1.110 (0.322–3.823) 0.869 0.751
(0.317–1.781)
.516 0.481 (0.158–1.467) 0.199 0.731 (0.407–1.31) .292
    3~4 / month 1.929 (0.989–3.763) 0.054 (0.066) 0.523 (0.056–4.865) 0.569 1.025 (0.172–6.098) .978 4.091 (0.474–35.342) 0.200 3.454 (1.256–9.5) 0.016
    > 1 / week 4.946 (2.005–12.198) 0.001 (0.002) 25.757 (1.902–348.864) 0.015 5.502 (0.536–56.471) .151 4.657 (0.442–49.076) 0.200 2.703 (0.638–11.452) .177
Type of skin care in salon
    Anti-aging 0.199 (0.077–0.514) 0.001 (0.002) N/Ab 0.368 (0.04–3.419) 0.380 0.081 (0.009–0.751) .027 0.229 (0.048–1.082) .063
    Oil-control 2.554 (1.241–5.256) 0.011 (0.017) 2.510 (0.114–55.432) 0.56 7.866
(0.361–171.275)
0.189 7.149 (1.209–42.273) .030 1.911 (1.692–5.278) .211
Frequency of make up
    Hardly 1 1 1 1 1
    1~2 / week 0.813 (0.501–1.32) 0.403 (0.45) 0.320 (0.042–2.451) 0.273 0.914 (0.297–2.818) .876 0.613 (0.181–2.077) .432 0.874 (0.425–1.796) .0714
    3~5 / week 1.193 (0.718–1.938) 0.495 (0.522) 1.027 (0.217–4.861) 0.974 0.159 (0.022–1.179) .072 0.585 (0.155–2.207) .429 2.520 (1.221–5.199) 0.012
    ≥ 6 / week 2.839 (1.962–4.018) <0.001 (<0.001) 2.422 (0.723–8.114) 0.152 5.200 (2.073–13.048) <0.001 1.331 (0.552–3.208) .524 3.015 (1.651–5.508) <0.001
Frequency of using sunscreen cream
    Hardly 1 1 1 1 1
    1~2 / week 0.507 (0.353–0.727) <0.001 (<0.001) 0.235 (0.044–1.253) .090 0.712 (0.303–1.673) 0.436 0.622 (0.277–1.394) 0.249 0.297 (0.165–0.534) <0.001
    3~5 / week 0.533 (0.328–0.867) 0.011 (0.017) 0.067 (0.008–0.595) .015 0.842 (0.257–2.76) 0.776 0.229 (0.057–0.922) 0.038 0.498 (0.241–1.03) 0.060
    ≥ 6 / week 0.303 (0.209–0.44) <0.001 (<0.001) 0.343 (0.097–1.21) .096 0.232 (0.085–0.632) 0.004 0.391 (0.163–0.934) 0.035 0.252 (0.144–0.442) <0.001

aThe p-value was adjusted by Bonferroni correction.

b The number of these cases was so small that not fit for calculating the OR value.