Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 23;15:2859–2872. doi: 10.2147/IJN.S249751

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Zhang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Effects of hucMSC-Exos on UV-induced damage in HDFs. (A) Confocal microscopic observation on the internalization of DiR-labeled hucMSC-Exos (red) by normal HDFs (stained with DAPI). (B) Effects of hucMSC-Exos on the proliferation of UV-irradiated HDFs (CCK-8 assay). (C) Effects of hucMSC-Exos on the expression of the biomarker for cellular senescence, SA-β-gal (blue staining). (D) Percentages of senescent cells in the photographs (C). (E) Numbers of cells in the photographs (C). (F) Effects of hucMSC-Exos on the mRNA expressions of dermal ECM-related genes in UV-irradiated HDFs. All data were expressed as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, versus the UV group; ^##p < 0.01, ^###p < 0.001, versus the control group.