Figure 10.
Psoralen could reverse cisplatin resistance of GC cells via activating the miR196a-HOXB7-HER2 Pathway. (A) Western blot results of HOXB7, HER2, Bcl-2 and CyclinD1 protein levels between MGC803 cells and MGC803/DDP cells following cultured with psoralen and the negative control. (B–E) The relative expression of HOXB7 (B), HER2 (C), Bcl-2 (D) and CyclinD1 (E) protein between MGC803 cells and MGC803/DDP cells following cultured with psoralen and the negative control was measured by WB. The beta-actin antibody was utilized for internal reference. Each assay was conducted in triplicate. ****P < 0.0001, ***P < 0.001 and mean±SD were utilized to show the data.