Table 3.
Neurological deterioration, mortality, recurrent vascular events, haemorrhagic transformation, and adverse events in patients with large artery occlusive disease
| Aspirin (n=173) | LMWH (n=180) | p | ||
|---|---|---|---|---|
| Neurological deterioration | ||||
| Day 2–9 | 8 (5%) | 10 (6%) | 0·69 | |
| Progressing stroke | 8 | 9 | ||
| Non-stroke neurological manifestation | 0 | 1 | ||
| Day 10 to month 6 | ||||
| Recurrent stroke | 9 (5%) | 8 (4%) | 0·74 | |
| Mortality | ||||
| Day 10 | 0 (0%) | 1 (1%) | 1·00 | |
| Month 6 [total patients assessed] | 8 (5%) [171] | 9 (5%) [179] | 0·88 | |
| Other vascular events by 6 months | ||||
| Acute coronary syndrome | 2 (1%) | 6 (3%) | 0·28 | |
| Deep vein thrombosis | 2 (1%) | 1 (1%) | 0·62 | |
| Pulmonary embolus | 0 (0%) | 0 (0%) | .. | |
| Haemorrhagic transformation on CT scan | 7 (4%) | 6 (3%) | 0·72 | |
| Symptomatic | 2 | 1 | ||
| Asymptomatic | 5 | 5 | ||
| Adverse event or severe adverse events | 83 (48%) | 87 (48%) | 0·95 | |
| Haemorrhagic adverse events | 15 (9%) | 25 (14%) | 0·12 | |
Data are numbers (%), unless otherwise indicated. LMWH=Low-molecular-weight heparin.