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. 2020 Apr 27;15(4):e0230406. doi: 10.1371/journal.pone.0230406

Table 1. Model fitting using individual and disease/epidemic-specific parameters.

Parameter Description 0–95 Days 95–186 Days 186–587 Days Source
Disease/Epidemic-specific parameters
N Size of the total population–Sierra Leone (2014) 7,017,144 World Bank Group [32]
SHCW HCW 1153 Evans et al. [33]
1/σ Mean latency period 7 days 7 days 7 days Legrand et al. [34]
1/γD Mean duration from death to burial 2 days 2 days 2 days Legrand et al. [34]
1/α Mean duration from onset of infection to hospitalization 2.4 days 2.4 days 2.2 days Fitted
βI→HCW Transmission rate from infectious individuals to HCW (In days−1) 117.8 15.0 5.1 Fitted
βH→HCW Transmission rate from hospitalized individuals to HCW (In days−1) 189.21 23.64 8.88 Fitted
βD→HCW Transmission rate from dead but not buried individuals to HCW (In days−1) 0.0726 0.0511 0.0450 Fitted
βI→NHCW Transmission rate from infectious individuals to the non-HCW/general population (In days−1) 0.635 0.594 0.425 Fitted
βH→NHCW Transmission rate from hospitalized individuals to the non-HCW/general population (In days−1) 0.0020 0.0010 0.0005 Fitted
βD→NHCW Transmission rate from dead but not buried individuals to the non-HCW/general population (In days−1) 0.0726 0.0511 0.0450 Fitted
δ1 Case-fatality rate among non-hospitalized infectious individuals 0.46 0.21 0.68 Fitted
δ2 Case-fatality rate among hospitalized individuals 0.46 0.21 0.68 Fitted
1/γ Mean duration from onset of infection to death/recovery 6 days 6 days 6 days Fitted
1/γH Mean duration from hospitalization to death/recovery 6.2 days 8.3 days 16 days Fitted
K1 Proportion of HCW in the total population at the start of the epidemic 0.016% Calculated

Abbreviations: HCW, healthcare workers; Non-HCW–overall population minus healthcare workers; WHO, World Health Organization