Table 1. Model fitting using individual and disease/epidemic-specific parameters.
Parameter | Description | 0–95 Days | 95–186 Days | 186–587 Days | Source | |
---|---|---|---|---|---|---|
Disease/Epidemic-specific parameters | ||||||
N | Size of the total population–Sierra Leone (2014) | 7,017,144 | World Bank Group [32] | |||
SHCW | HCW | 1153 | Evans et al. [33] | |||
1/σ | Mean latency period | 7 days | 7 days | 7 days | Legrand et al. [34] | |
1/γD | Mean duration from death to burial | 2 days | 2 days | 2 days | Legrand et al. [34] | |
1/α | Mean duration from onset of infection to hospitalization | 2.4 days | 2.4 days | 2.2 days | Fitted | |
βI→HCW | Transmission rate from infectious individuals to HCW (In days−1) | 117.8 | 15.0 | 5.1 | Fitted | |
βH→HCW | Transmission rate from hospitalized individuals to HCW (In days−1) | 189.21 | 23.64 | 8.88 | Fitted | |
βD→HCW | Transmission rate from dead but not buried individuals to HCW (In days−1) | 0.0726 | 0.0511 | 0.0450 | Fitted | |
βI→NHCW | Transmission rate from infectious individuals to the non-HCW/general population (In days−1) | 0.635 | 0.594 | 0.425 | Fitted | |
βH→NHCW | Transmission rate from hospitalized individuals to the non-HCW/general population (In days−1) | 0.0020 | 0.0010 | 0.0005 | Fitted | |
βD→NHCW | Transmission rate from dead but not buried individuals to the non-HCW/general population (In days−1) | 0.0726 | 0.0511 | 0.0450 | Fitted | |
δ1 | Case-fatality rate among non-hospitalized infectious individuals | 0.46 | 0.21 | 0.68 | Fitted | |
δ2 | Case-fatality rate among hospitalized individuals | 0.46 | 0.21 | 0.68 | Fitted | |
1/γ | Mean duration from onset of infection to death/recovery | 6 days | 6 days | 6 days | Fitted | |
1/γH | Mean duration from hospitalization to death/recovery | 6.2 days | 8.3 days | 16 days | Fitted | |
K1 | Proportion of HCW in the total population at the start of the epidemic | 0.016% | Calculated |
Abbreviations: HCW, healthcare workers; Non-HCW–overall population minus healthcare workers; WHO, World Health Organization