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. Author manuscript; available in PMC: 2020 Apr 27.
Published in final edited form as: Pediatr Hematol Oncol. 2017 Dec 4;34(5):331–342. doi: 10.1080/08880018.2017.1396386

TABLE 2.

Chemotherapy Combinations and Incidence of Infection and Febrile Neutropenia following that combination

Chemotherapy Combination Number of Cycles Administered Incidence of Infection Incidence of FN
Vincristine/Doxorubicin/Cyclophosphamide 147 25.9% 42.2%
Cisplatin/Etoposide 87 20.7% 33.3%
Ifosfamide/Etoposide 66 15.2% 9.1%
Carboplatin/Etoposide 62 12.9% 9.7%
Other 4 25% 25%

Cisplatin/Etoposide: Cisplatin 40 mg/m2/day x 5 days, Etoposide 200 mg/m2 × 3 days

Vincristine/Doxorubicin/Cyclophosphamide: Vincristine 1.5 mg/m2 × 1 day, Doxorubicin 60 mg/m2 × 1 day, Cyclophosphamide 2000 mg/m2 × 2 days

Ifosfamide/Etoposide: Ifosfamide 1800 mg/m2 × 5 days, Etoposide 100 mg/m2 × 5 days

Carboplatin/Etoposide: Carboplatin 500 mg/m2 × 2 days, Etoposide 150 mg/m2 × 3 days