TABLE 3.

Univariate analyses for all infections, blood stream infections only, and febrile neutropenia

		All infections			Blood Stream Infection			Febrile Neutropenia
		RR	95% CI	P	RR	95% CI	P	RR	95% CI	P
Sex	Male
	Female	1.4	0.33–2.39	0.009	0.45	−0.59–1.4	0.35	−1.1	−0.01–2.21	0.052
Race/Ethnicity	NHW
	HW	1.15	0.12–2.42	0.076	0.16	−0.98–1.31	0.78	−1.2	−0.002–2.57	0.05
	NHB	−0.1	−1.2–1.5	0.88	0.62	−0.78–2.02	0.39	0.46	−2.7–1.77	0.69
	NH-other	n/a			n/a			n/a
	Unknown	−0.6	−0.72–0.52	0.44	0.11	−1.46–1.68	0.89	−1.22	−0.45–2.89	0.15
Payer	Medicaid
	Private	−1.32	−2.36- −0.29	0.01	−0.68	−1.7–0.34	0.19	1.35	0.14–2.57	0.03
	Other	1.03	−3.28–1.22	0.37	1.39	−0.38–3.15	0.12	0.51	−1.26–2.28	0.57
Age (years)	<3
	>3	−1.37	−2.37 - −0.375	0.007	−0.63	−1.57–0.31	0.18	−0.1	−1.05–1.14	0.93
MYCN amplification	Non-amplified
	Amplified	1.32	0.32–2.32	0.009	1.39	0.36–2.42	0.008	0.16	−0.94–1.25	0.78
	Unknown	1.09	0.72–2.93	0.24	0.52	−1.35–2.4	0.54	−16	−4658–4625	0.99
Era of Diagnosis	2002–2008
	2009–2015	−0.73	−1.65–0.19	0.12	−1.1	−2.1- −0.12	0.027	0.32	−0.76–1.42	0.56
Line type	Totally implantable
	External (PICC, DL tunneled or pharesis) *	0.91	−0.12–1.96	0.09	2.13	0.57–3.67	0.007	−1.19	−2.76–0.38	0.14
Received TPN	No
	Yes	0.81	−0.18–1.81	0.112	1.002	0.21–1.98	0.045	0.66	−0.58–1.89	0.29

^*refers to patient having external line at any point in induction therapy

refers to patient having external line at any point in induction therapy

Abbreviations: RR: Relative risk; DL: double lumen; NHW: Non-Hispanic White; HW: Hispanic White; NHB: Non-Hispanic Black; NH-other: Non-Hispanic Other; PICC: Peripherally-inserted central catheter; TPN: Total parenteral nutrition