Table 1.

Screening approaches to identify novel cellular factors affecting viral replication (selected publications)

Global viral screens	Influenza	Genomics	[2, 3••, 4, 5, 6•, 7, 81, 82]
		Proteomics and genomics	[15, 16]
	HIV	Genomics	[9, 8••, 83, 10, 11, 12, 84, 85]
		Phosphoproteomics cellular reprogramming through HIV	[26•]
		Proteomics	[13••]
	Other viruses	Genomics	HCV [86, 87] Dengue [88] WNV [89]
		Proteomics	KSHV [14] Herpesvirus [90]
		Proteomics and genomics	HCV [17]
Effectors of antiviral response	Genomics	HCV, YFV, WNV, chikungunya virus, Venezuelan equine encephalitis virus, HIV [63••] various ds DNA, (+)ssRNA, (−)ssRNA viruses [19] VSV, MHV-68 [91]
	Genomics combined with IFN stimulation	HCV [92] HCV [93]
	Proteomics and genomics	Many different RNA and DNA virus ORFs [18]
Cellular reprogramming/rewiring through viruses	Phospho-proteomics	HIV [26•]
	Proteomics	HPV, EBV, Ad5 and PyV [94]
Innate immune response pathway members affecting viral replication	Cytosolic DNA pathway	Proteomics and genomics	HIV [20]
	Type I interferon regulation	Proteomics and genomics	VSV, Sendai, HSV [23]
	TLR pathway	Genomics	Sendai [22]
		Transcriptmomics, genetic perturbations, phosphoproteomics	EMCV, NDV, VSV, Influenza [21]
In vivo screening approach	Genomics	[75]