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Inhibition of chymotrypsin by peptide aldehyde and peptide glyoxal inhibitors at pH 7.2: Contribution of the aldehyde and glyoxal groups to inhibition.
| Inhibitor | Ki(obs) (μM) | KiZAAF-H/KiZAAF-CHO | KiZAAF-H/KiZAAF-COCHO |
|---|---|---|---|
| ZAAF-H | 170 ± 10a | ||
| ZAAF-CHO | 1.7 ± 0.4a | 100 | |
| ZAAF-COCHO | 0.37b | 460 |
Present work, errors are the standard deviations of 3 or more determinations.
