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. 2020 Apr 27;146(7):1737–1749. doi: 10.1007/s00432-020-03228-4

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© Springer-Verlag GmbH Germany, part of Springer Nature 2020

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Fig. 1 — Morphology and resistance of cisplatin-resistant cell lines H358^R and A549^R. a H358^R and A549^R cell lines showed irregular long spindles, flat, and blurred borders compared to their parental cell lines. b Cells were treated by a range of increasing cisplatin concentrations for 48 h and IC₅₀ was calculated as described by Chou and colleagues with MTT assay (*P < 0.05, **P < 0.01)