Fig. 5.

Gefitinib (GFB) combined with cisplatin (cis) significantly inhibits proliferation of H358^R and A549^R cells. a Inhibition ratio of cells incubated with cisplatin (cis), gefitinib (GFB), or a combination of two drugs for 48 h, was measured with MTT assay. b Proliferation inhibition of cells incubated with cisplatin (cis), gefitinib (GFB), or a combination of two drugs for 24 h, was measured with clone formation assay. c Expression of related proliferation regulation protein in H358^R and A549^R cells incubated with cisplatin (cis), gefitinib (GFB), or a combination of two drugs for 48 h, was detected by western blot (*P < 0.05, **P < 0.01)