Table 3.

Specificity and time to detection for five algorithms based on the optimize combinations of parameter value.

Algorithms	Specificity (%)		Time to detection (d)
	Mean	${\chi }^2$ Test lower CI	Mean	${\chi }^2$ Test lower CI
EWMA (0.7, 3.0)	95.2	<0.001	0.1	>0.0125
C1′ (0.4, 5σ)	95.7	<0.001	1.0	<0.001
C2′ (0.5, 4σ)	89.2	<0.001	0.8	<0.001
C3′ (0.8, 3σ)	73.7	<0.001	0.7	<0.001
Space–time permutation scan statistic (3d, 2 km) ⁎	99.9	—	0.2	—

^⁎Space–time permutation scan served as control group. According to Bonferroni’s procedure, the family wise error rate was 0.05, divided by the number of test. The significance level α for an individual test was 0.05/4, being 0.0125.