Fig. 5.

Dynamic contrast-enhanced MRI data during longitudinal study, representative 3-D angiogram from micro-CT-based angiography and examination of perfused leakage particles for micro-CT-based angiography. Difference in representative dynamic contrast-enhanced MRI derived time-intensity curve at week 1 post-induction between the H-ICT group with high peak enhancement percentage (A) and the CON group with low peak enhancement percentage (B). (C) At week 1 post-induction, the significantly decreased PEP in the CON group was attenuated in the L-ICT group and prevented in the H-ICT group. (D) Throughout the experimental period, the significantly increased PSρ in the CON group were attenuated in the L-ICT group and almost prevented in the H-ICT group.