Figure 2.

More than 50% of the unique transcripts with a change in expression in response to electroacupuncture had one or several CpG sites annotated to the gene with a change in DNA methylation. CpG sites (P < 0.05) with a change in DNA methylation annotated to genes with altered expression (q < 0.05). Values are change before vs after electroacupuncture presented as % points for CpG site methylation and % change in gene expression presented next to each gene name. All altered CpG methylation sites of genes with changes in mRNA expression in response to electroacupuncture were calculated based on linear regression analyses and are presented in Supplementary Table S4 (30).