Table 1.
Characteristics of Women With PCOS and Controls Matched for Age, Weight and Body Mass Index. Cohort Has Been Previously Published (22)
Variable | Controls (n = 14) | PCOS (n = 15) | P |
---|---|---|---|
Age (y) | 29.7 ± 5.8 | 30.7 ± 5.5 | 0.683 |
Body composition | |||
Body mass index (kg/m2) | 30.2 ± 3.6 | 30.9 ± 4.5 | 0.591 |
Weight (kg) | 85.0 ± 12.2 | 85.1 ± 14.3 | 0.949 |
Height (cm) | 167.6 ± 8.45 | 166.0 ± 8.2 | 0.747 |
Waist-to-hip ratio | 0.82 ± 0.06 | 0.85 ± 0.07 | 0.270 |
Clinical reproductive | |||
Antral follicle < 9mm (n) | 8.07 ± 4.91 | 22.36 ± 6.72 | <0.000 |
Ovarian volume (cm3) | 4.68 ± 2.47 | 9.32 ± 6.32 | 0.006 |
Oligoamenorrhea/Amenorrhea, n (%) | 0 (0) | 13 (87) | na |
Regular, n (%) | 14 (100) | 2 (13) | na |
Ferriman Gallwey score | 1.43 ± 1.40 | 10.60 ± 6.59 | <0.000 |
Acne (yes), n (%) | 2 (14.3) | 7 (46.7) | na |
Endocrine variables | |||
Apolipoprotein A1 (ApoA1) (g/l) | 1.46 ± 0.18 | 1.46 ± 0.22 | 1.000 |
Apolipoprotein B (ApoB) (g/l) | 0.82 ± 0.17 | 0.85 ± 0.27 | 0.983 |
ApoA1/ApoB ratio | 0.56 ± 0.12 | 0.61 ± 0.18 | 0.591 |
Cholesterol (mmol/l) | 4.34 ± 0.89 | 4.73 ± 1.40 | 0.451 |
Triglycerides (mmol/l) | 0.86 ± 0.31 | 1.15 ± 0.55 | 0.112 |
B-Hba1c (mmol/mol) | 31.57 ± 2.77 | 32.00 ± 2.78 | 0.683 |
Glucose (mmol/l) | 5.13 ± 0.44 | 4.82 ± 0.34 | 0.051 |
Insulin (mU/l) | 9.05 ± 3.83 | 12.81 ± 8.67 | 0.310 |
C-peptide (ng/ml) | 0.86 ± 0.35 | 1.17 ± 0.49 | 0.057 |
C-peptide index | 5.74 ± 2.63 | 8.16 ± 3.74 | 0.062 |
HOMA-IR | 2.02 ± 1.02 | 3.10 ± 2.28 | 0.234 |
HOMA-B | 124.3 ± 71.3 | 201.9 ± 156.4 | 0.186 |
Glucose disposal rate (mg × kg-1 x min-1) | 7.47 ± 2.98 | 6.46 ± 3.11 | 0.270 |
Reproductive variables | |||
Testosterone (pg/ml) | 262.0 ± 70.9 | 475.3 ± 190.2 | 0.000 |
17α-hydroxyprogesterone (nmol/l) | 3.11 ± 1.93 | 2.43 ± 1.02 | 0.505 |
Luteinizing hormone (LH) (IU/l) | 5.59 ± 2.97 | 8.13 ± 5.72 | 0.425 |
Follicle stimulating hormone (FSH) (IU/L) | 5.66 ± 3.42 | 4.09 ± 1.31 | 0.123 |
LH/FSH ratio | 1.18 ± 0.84 | 1.95 ± 1.17 | 0.158 |
Sex hormone binding globulin (nmol/liter) | 45.29 ± 27.45 | 37.07 ± 15.81 | 0.505 |