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. 2020 Apr 1;31(8):782–792. doi: 10.1091/mbc.E19-09-0495

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© 2020 Feng et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 6: — p150 shortens diffusive segments and elongates processive segments. (A) Cumulative distributions of processive, diffusive, and stuck segment durations for control DDB. Mean durations were 0.81 s for processive, 0.23 s for diffusive, and 0.53 s for stuck states. Inset: Number of detected state switches over 93 s total analyzed time from 31 molecules. (B) State switching diagram showing first-order switching rates between states and the fraction of time spent in each state for control DDB. The blue arrow denotes the most significant decrease in switching rate with Ab_p150, while the red arrow denotes the most significant increase in switching rate. (C) Cumulative distributions of processive, diffusive, and stuck segment durations for DDB in the presence of Ab_p150. Mean durations were 0.61 s for processive, 0.37 s for diffusive, and 0.60 s for stuck states. Inset: number of detected state switches for the Ab_p150 group over 100 s total analyzed time from 32 molecules. (D) State switching diagram showing first-order switching rates between states and the fraction of time spent in each state DDB in the presence of Ab_p150.