Figure 2. Differential expression (Log2FoldChange) of genes up-regulated in sound root surface (SRS; negative values, green bars) and up-regulated in root caries (RC, positive values, red bars) calculated using DESeq2 algorithms. FDR<0.05. GUT1= potential glycerol kinase; STT4= hypothetical protein phosphatidylinositol-4-kinase; CaO19.7838= flocullin-like protein serine-rich; CaO19.7197= hypothetical protein; DHN6= dehydrin hypothetical protein; ITR1= potential Myo-inositol transporter; UTP20= potential U3 small nucleolar RNAs protein; CaO19.2506= hypothetical protein with a very weak similarity to Streptoccal proline-rich surface protein PspC; CaO19.610= potential DNA binding regulator of filamentous growth.