Skip to main content
. 2020 Apr 28;104(12):5243–5257. doi: 10.1007/s00253-020-10641-9

Table 2.

Functional roles of bioactive peptides synthesized by aminopeptidases

Bioactive peptides Functional applications Reference
Pro-containing peptides Nutraceutical properties Yamamoto et al. 2010
Pro-Hyp Stimulates growth of fibroblasts from mouse skin Shigemura et al. 2009
Pro-Arg Defensive activity against oxidative stress and cell damage Meyer et al. 2009

Val-Pro-Pro

Ile-Pro-Pro

Angiotensin I-converting enzyme inhibition Meyer et al. 2009
Cyclo (Pro-Pro) Antibacterial activity against Micrococcus luteus and Pseudomonas aeruginosa Huberman et al. 2007
Cyclo (Pro-Phe) Caspase 3 activation Brauns et al. 2005
Bioactive peptides from skimmed milk hydrolysate Angiotensin-converting enzyme inhibition Pan et al. 2005
Bioactive peptides from whey protein hydrolysates Angiotensin-converting enzyme inhibition Cheung et al. 2015