Table 3.

List of patents developed on microbial aminopeptidases

Patent no.	Organism	Aminopeptidase	Application	Reference
WO 96/28542	Aspergillus oryzae	Leucine AP	Reduction of bitter taste in protein hydrolysate	Kauppinen 1996
US 6,271,013 B1	Aspergillus niger	Phenylalanine AP Leucine AP valine AP	Food industry in the preparation of bread dough or cheese	Chevalet et al. 2001
EP 2206 777B1	Aminopeptidase gene in Vibrio proteilytica cloned in E.coli	Aminopeptidase P	Selectively remove N-terminal amino acids when the penultimate residue is proline. Used in the production of medicines and food stuff, in particular proteins such as human growth hormone, G-CSF, and IL-2	Sonoda et al. 2014
US 7,098,018 B2	Recombinant Bacillus licheniformis aminopeptidase	Methionine AP	Enzymatic preparation of industrially important protein such as human growth hormones	Lee et al. 2006
US 3,405,034	Aspergillus	Leucine AP	Protein hydrolysis	Wenzel et al. 1968
US 5,013,662	Escherichia coli	Methionine AP	N-terminal methionine processing	Ben-Bassat et al. 1991
WO 97/04108	Aspergillus sojae	Leucine AP	Preparation of protein hydrolysate	Schuster et al. 1997
US 6,127,161	Aspergillus sojae	Leucine AP	Food products such as seasoning	Umitsuki and Abe 2000
EP 1,629,719 A1	Aspergillus nidulans	Glutamyl/aspartyl AP	Producing foods and/or beverages having improved taste and/or flavor	Tomohiro et al. 2006