Table 2.
Univariate and Multivariate Analyses of Liver Failure in Patients With Hepatitis E
| Parameter | OR (95% CI) | P | aOR (95% CI) | P |
|---|---|---|---|---|
| Male sex | 4.235 (0.974–18.410) | .054 | 2.425 (0.614–9.581) | .206 |
| Age ≥53 y | 1.474 (0.711–3.056) | .297 | - | - |
| Cirrhosis | 4.108 (1.979–8.528) | <.001 | 6.050 (1.814–20.179) | .003 |
| Etiology of CLD | ||||
| No-CLD | Reference | - | Reference | - |
| ALD | 2.255 (0.897–5.672) | .084 | 0.858 (0.267–2.757) | .797 |
| CHB | 2.515 (0.992–6.379) | .052 | 0.561 (0.135–2.325) | .426 |
| CHB + ALD | 1.817 (0.190–17.354) | .604 | 0.743 (0.068–8.117) | .808 |
| Othersa | 1.384 (0.418–4.585) | .595 | 0.317 (0.063–1.589) | .162 |
Abbreviations: ALD, alcoholic liver disease; aOR, adjusted odds ratio; CHB, chronic hepatitis B; CI, confidence interval; CLD, chronic liver disease; OR, odds ratio.
aOther etiologies of CLD included nonalcoholic fatty liver disease, combination of alcoholic liver disease and autoimmune liver disease, cryptogenic cirrhosis, combination of chronic hepatitis B–related cirrhosis and hepatocellular carcinoma, drug-induced liver injury–related cirrhosis, primary biliary cirrhosis, hepatitis C virus–related cirrhosis, and combination of primary biliary cirrhosis and autoimmune cirrhosis.