Table 3.
Results from three-level hierarchal generalized logistic model (HGLM) analysis predicting odds of leukodystrophy (n=1,070,062 children)
| Odds | |||||
|---|---|---|---|---|---|
| Coeff. | Ratio | SE | t-ratio | p-value | |
| Hospital Level | |||||
| Intercept | −7.761 | 0.0004 | 0.076 | −101.76 | <0.001 |
| Center of Excellence | 0.550 | 1.734 | 0.064 | 8.539 | <0.001 |
| Hospital months | 0.011 | 1.011 | 0.009 | 1.312 | 0.196 |
| Zip Code Level | |||||
| Median household income | 0.0002 | 1.0000 | 0.0002 | 1.107 | 0.268 |
| HPSA flag | −0.149 | 0.862 | 0.058 | −2.547 | 0.011 |
| Distance to hospital | 0.0007 | 1.0007 | 0.0001 | 5.247 | <0.001 |
| Proportion non-White | −0.539 | 0.583 | 0.174 | −3.102 | 0.002 |
| Urban/Rural Context | |||||
| Urban core | REF | REF | REF | REF | |
| Large rural | 0.169 | 1.184 | 0.066 | 2.552 | 0.011 |
| Small rural | 0.280 | 1.323 | 0.077 | 3.617 | <0.001 |
| Isolated | 0.470 | 1.600 | 0.113 | 4.171 | <0.001 |
| Other urban | −0.028 | 0.973 | 0.060 | −0.457 | 0.648 |
| Patient Level | |||||
| Age at first admit in study period | 0.020 | 1.020 | 0.003 | 6.121 | <0.001 |
| Male (versus female) | 0.299 | 1.348 | 0.048 | 6.192 | <0.001 |
| Inpatient days (per time in PHIS) | 0.385 | 1.470 | 0.113 | 3.395 | <0.001 |
| Number of admits (per time in PHIS) | 1.435 | 4.200 | 0.133 | 10.784 | <0.001 |
| Patient Race/Ethnicity | |||||
| White, non-Hispanic | REF | REF | REF | REF | |
| Hispanic | 0.013 | 1.0133 | 0.061 | 0.216 | 0.829 |
| Black, non-Hispanic | −0.415 | 0.660 | 0.064 | −6.530 | <0.001 |
| Asian, non-Hispanic | −0.349 | 0.706 | 0.160 | −2.172 | 0.030 |
| Other race, Non-Hispanic | 0.172 | 1.188 | 0.063 | 2.722 | 0.006 |
| Patient Payer Status | |||||
| Private payer | REF | REF | REF | REF | |
| Government payer | 0.374 | 1.554 | 0.046 | 9.559 | <0.001 |
| Other payer | 0.374 | 1.1454 | 0.117 | 3.198 | 0.001 |