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. 2020 Apr 27;11(4):294. doi: 10.1038/s41419-020-2475-3

Fig. 6. miR-548t-5p suppresses cell proliferation and metastasis by targeting CXCL11.

Fig. 6

ad EdU assay was performed to analyze proliferation in BXPC-3-miR-548t-5p inhibitor cells transfected with CXCL11 siRNA and PANC-1-miR-548t-5p-mimics cells transfected with CXCL11-overexpression vector. Magnification, ×100; scale bar, 100 μm in a and c. e, f Wound-healing assays were performed to analyze migration in BXPC-3-miR-548t-5p inhibitor cells transfected with CXCL11 siRNA and PANC-1-miR-548t-5p-mimics cells transfected with CXCL11-overexpression vector. Magnification, ×100; scale bar, 100 μm. g, h Transwell assays were performed to analyze migration in BXPC-3-miR-548t-5p inhibitor cells transfected with CXCL11 siRNA and PANC-1-miR-548t-5p-mimics cells transfected with CXCL11-overexpression vector. Magnification, ×100; scale bar, 100 μm. The data are presented as mean ± SD from three independent experiments. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001.