Table 1.
Demographics, aSAH risk factors, and periodontitis in the studied intracranial aneurysm patients from Kuopio University Hospital (KUH IA patients). Data is presented as median and range or as proportions with 95%CI
| Variable | aSAH (n = 33) | No aSAH (n = 41) | p value | Matched controls (n = 70) | p value |
|---|---|---|---|---|---|
| Age | 50.0 (27.0–76.0) | 60.0 (22.0–77.0) | 0.004 | 57.0 (31.0–76.0) | NS |
| Gender (number of females) |
23/33 (69.7%, 95%CI 51.1–83.8) |
25/41 (61.0%, 95%CI 44.6–75.4) |
NS |
45/70 (64.3%, 95%CI 51.9–75.1) |
NS |
| IA family history |
5/33 (15.2%, 95%CI 5.7–32.7) |
6/41 (14.6%, 95%CI 6.1–29.9) |
NS | ||
| Multiple IAs |
17/33 (51.5%, 95%CI 33.9–68.8) |
17/41 (41.5%, 95%CI 26.7–57.8) |
NS | ||
| Hypertension (treated with medication) |
16/33 (48.5%, 95%CI 31.2–66.1) |
23/41 (56.1%, 95%CI 39.9–71.2) |
NS |
40/70 (57.1%, 95%CI 44.8–68.7) |
NS |
| Untreated or inadequately treated hypertension |
3/33 (9.1%, 95%CI 2.4–25.5) |
0/41 | NS | ||
| Diabetes (type I or II) | 0/33 |
3/41 (7.3%, 95%CI 1.9–21.0) |
NS | ||
| Heavy alcohol consumption (defined by treating physician) |
1/33 (3.0%, 95%CI 0.2–17.5) |
3/41 (7.3%, 95%CI 1.9–21.0) |
NS | ||
| Current smoking |
16/33 (48.5%, 95%CI 31.2–66.1) |
10/41 (24.4%, 95%CI 12.9–40.6) |
0.047 |
26/70 (37.1%, 95%CI 26.1–49.6) |
NS |
| No smoking history |
16/33 (48.5%, 95%CI 31.2–66.1) |
23/41 (56.1%, 95%CI 39.9–71.2) |
0.047 | ||
|
Periodontitis (≥ 4 mm periodontal pocket) |
31/33 (93.9%, 95%CI 78.4–98.9) |
37/41 (90.2%, 95%CI 75.9–96.8) |
NS |
47/70 (67.1%, 95%CI) |
< 0.001 |
|
Periodontitis (periodontal pocket 4–5 mm) |
15/33 (45.5%, 95%CI 28.5–63.4) |
17/41 (41.5%, 95%CI 26.7–57.8) |
NS NS |
29/70 (41.4%, 95%CI 30.0–53.8) |
< 0.001 |
|
Severe periodontitis (≥ 6 mm periodontal pocket) |
16/33 (48.5%, 95%CI 31.2–66.1) |
20/41 (48.8%, 95%CI 33.2–64.6) |
18/70 (25.7%, 95%CI 16.3–37.8) |
< 0.001 | |
| Mean BOP % | 40.1% | 37.9% | NS | ||
| Number of bleeding sextants | |||||
| 0–1 |
1/33 (3.0%, 95%CI 0.2–17.5) |
2/41 (4.9%, 95%CI 0.9–17.8) |
NS |
39/70 (55.7%, 95%CI 43.4–67.4) |
< 0.001 |
| 2–3 |
6/33 (18.2%, 95%CI 7.6–36.1) |
11/41 (26.8%, 95%CI 14.8–43.2) |
NS |
18/70 (25.7%, 95%CI 16.3–37.8) |
< 0.001 |
| 4–6 |
26/33 (78.8%, 95%CI 60.6–90.4) |
28/41 (68.3%, 95%CI 51.8–81.4) |
NS |
13/70 (18.6%, 95%CI 10.6–30.0) |
< 0.001 |
| Gingival bleeding from teeth sextants (mean sextants affected) | 4.8 | 4.3 | NS | 1.0 | < 0.001 |