Fig. 6.

Cre-mediated recombination in the organs of astrocyte-specific CreER^T2:Ai14 transgenic mice. A–F Recombination in the lung (A), myocardium (B), liver (C), spleen (D), intestine (E), and muscle (F) in Aldh1l1-, Glast-, Cx30-, and Fgfr3-i CreER^T2:Ai14 mice (scale bars, 100 µm). G–J Representative high-magnification images of lung in the Aldh1l1-, Glast-, Cx30-, and Fgfr3-i CreER^T2:Ai14 mice. Two morphologically distinct cell types, round (triangles) and branching cells (pentagons), were sparsely distributed in the Aldh1l1-CreER^T2:Ai14 mice (G) but densely distributed in the Fgfr3-i CreER^T2:Ai14 mice (J); however, only branching cells were observed in the Glast-CreER^T2:Ai14 mice (H), and only round cells in the Cx30-CreER^T2:Ai14 mice (I) (scale bars, 50 µm).