Table 1.

Astroglia-specific induction of Cre recombination by tamoxifen (%).

Brain region	GFAP		S100β		NeuN		Iba1		Olig2
	Efficiency	Specificity	Efficiency	Specificity	Efficiency	Specificity	Efficiency	Specificity	Efficiency	Specificity
Olfactory bulb	–	–	57.84 ± 7.62	77.84 ± 0.36	0	0	1.38 ± 0.36	0.81 ± 0.13	6.1 ± 4.01	7.42 ± 4.51
Cortex	–	–	54.05 ± 1.41	96.12 ± 1.37	0.09 ± 0.01	0.59 ± 0.07	1.57 ± 0.43	1.23 ± 1.51	2.58 ± 1.46	4.23 ± 1.29
Hippocampus	66.86 ± 1.48	95.84 ± 1.02	64.75 ± 1.32	97.51 ± 1.3	0	0	2.44 ± 1.79	1.51 ± 0.85	1.64 ± 0.7	2.38 ± 1.31
BLA	–	–	62.96 ± 2.72	96.94 ± 1.51	0	0	1.30 ± 1.54	1.15 ± 1.40	3.17 ± 1.94	4.55 ± 2.01
PFC	–	–	59.75 ± 2.41	96.71 ± 0.24	0	0	1.67 ± 1.13	1.52 ± 1.44	2.98 ± 1.68	3.15 ± 1.88
VTA			53.57 ± 3.58	95.6 ± 1.09	0	0	2.71 ± 1.01	2.14 ± 1.94	2.95 ± 1.62	3.44 ± 1.28
Thalamus	–	–	95.28 ± 2.64	97.16 ± 1.18	0	0	3.57 ± 1.8	2.63 ± 1.51	3.21 ± 1.93	3.98 ± 1.75
Hypothalamus	69.01 ± 3.75	44.67 ± 6.02	61.03 ± 7.7	76.37 ± 1.6	0	0	3.92 ± 0.94	2.82 ± 1.45	3.08 ± 1.55	3.81 ± 1.42
Midbrain	–	–	64.82 ± 3.77	95.39 ± 2.48	0	0	1.97 ± 1.54	1.55 ± 1.81	2.96 ± 1.08	3.17 ± 1.26
Cerebellum (Bergmann glia)	–	–	92.17 ± 0.41	97.29 ± 1.49	0	0	2.53 ± 0.53	1.91 ± 0.47	2.24 ± 1.06	2.51 ± 1.67
Medulla	–	–	50.23 ± 0.63	90.54 ± 2.59	0	0	0.88 ± 0.15	0.92 ± 0.36	2.85 ± 1.92	3.11 ± 1.83
Spinal cord	79.18 ± 4.76	56.17 ± 2.57	46.94 ± 3.38	78.51 ± 7.15	0	0	2.40 ± 0.61	1.69 ± 0.63	1.84 ± 1.05	2.47 ± 1.68

Aldh1l1-CreER^T2:Ai14 transgenic mice were induced by tamoxifen, and immunofluorescence with GFAP, S100β, NeuN and Iba1, then imaged by confocal laser scanning microscopy. The specificity of Cre recombinase activity was defined as the number of marker- and tdTomato-positive cells divided by the total number of tdTomato⁺ cells. The efficiency was defined as the number of tdTomato⁺ cells divided by the total number of marker-positive cells. Data are shown as mean ± SEM, n = 3.