Table 1.
Baseline characteristics of the study population (n = 296) according to GA levels.
| Lower GA group (GA <16.0%) n = 79 | Higher GA group (GA ≥ 16.0%) n = 217 | p-value | |
|---|---|---|---|
| Age, years (SD) | 70.8 (11.8) | 70.2 (11.4) | 0.67† |
| Male (%) | 44 (55.7) | 131 (60.4) | 0.51* |
| BMI, kg/m2 (SD) | 24.2 (3.4) | 24.5 (3.7) | 0.82† |
| Interval from onset to visit, hours [median (IQR)] | 14.8 (5.3–50.0) | 12.9 (3.7–38.4) | 0.35‡ |
| History of stroke (%) | 23 (29.1) | 59 (27.2) | 0.77* |
| Hypertension (%) | 64 (81.0) | 158 (72.8) | 0.17* |
| Duration of DM, year (SD) | 7.3 (2.7) | 5.2 (2.7) | 0.18† |
| Hyperlipidemia (%) | 17 (21.5) | 34 (15.7) | 0.30* |
| Current smoking (%) | 12 (15.2) | 28 (12.9) | 0.70* |
| Atrial fibrillation (%) | 15 (19.0) | 39 (18.0) | 0.87* |
| Coronary artery disease (%) | 6 (7.6) | 20 (9.2) | 0.82* |
| Prior antithrombotic agents (%) | 41 (51.9) | 96 (44.2) | 0.29* |
| Initial NIHSS score (IQR) | 4 (2–6) | 5 (2–11) | 0.052‡ |
| Stroke mechanism (%) | 0.14* | ||
| SVO | 27 (34.2) | 51 (23.5) | |
| LAA | 28 (35.4) | 97 (44.7) | |
| CE | 16 (20.3) | 35 (16.1) | |
| Others | 8 (10.1) | 34 (15.7) | |
| Reperfusion therapy (%) | 9 (11.4) | 28 (12.9) | 0.84* |
| Ischemic lesions (%) | 0.92* | ||
| Supratentorial | 53 (67.1) | 147 (67.7) | |
| Infratentorial | 26 (32.9) | 70 (32.3) | |
| Laboratory data | |||
| Total cholesterol, mg/dL (SD) | 153.8 (46.9) | 155.2 (43.0) | 0.51† |
| Hemoglobin, g/dL (SD) | 13.1 (1.9) | 13.5 (2.2) | 0.48† |
| Creatinine, mg/dL (SD) | 1.1 (0.9) | 1.1 (0.6) | 0.33† |
| Platelets, ×1,000/μL (SD) | 228.3 (70.2) | 228.1 (80.3) | 0.51† |
| hs-CRP, mg/L (SD) | 10.8 (27.4) | 12.3 (28.8) | 0.66† |
| LDL, mg/dL (SD) | 51.3 (31.4) | 45.9 (31.6) | 0.38† |
| HbA1c, % (SD) | 6.3 (1.0) | 7.6 (1.5) | 0.002† |
| Initial random glucose, mg/dL (SD) | 150.6 (55.9) | 182.7 (74.1) | 0.02† |
| Serum albumin, mg/dL (SD) | 3.88 (0.30) | 3.85 (0.42) | 0.08† |
| SBP, mmHg (SD) | 150.0 (26.4) | 148.6 (25.2) | 0.43† |
| Infarct volume, cm3, median (IQR) | 0.46 (0.21–2.21) | 1.77 (0.41–33.15) | <0.001 |
GA, glycated albumin; SD, standard deviation; BMI, body mass index; IQR, interquartile range; DM, diabetes mellitus; NIHSS, National Institute Health of Stroke Scale; SVO, small vessel occlusion; LAA, large artery atherosclerosis; CE, cardioembolism; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; HbA1c, glycated hemoglobin; SBP, systolic blood pressure.
*
Calculated using the chi-square test.
†
Calculated using Student's t-test.
‡
Calculated using Mann-Whitney U test.