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. 2020 Apr 21;8:180. doi: 10.3389/fped.2020.00180

Figure 2.

Figure 2

Plasma concentrations of inflammatory biomarkers in prepubertal children with a history of extrauterine growth restriction (EUGR, N = 38), prepubertal children with prematurity without EUGR (PREM, N = 50) and prepubertal healthy children born at term (Control, N = 123). (A) TNF-α, tumor necrosis alpha; (B) HGF, hepatocyte growth factor; (C) MCP-1, monocyte chemotactic protein type 1; (D) CRP, C-reactive protein; (E) IL-8, interleukin 8; (F) PAI-1, plasminogen activator inhibitor type 1; (G) IL-6, interleukin 6; (H) NGF, neural growth factor. Values are medians, with their interquantile ranges represented by vertical bars. *Value was significantly different from that of the PREM group with p-value < 0.005. **Value was significantly different from that of the CONTROL group with p-value < 0.005 (Mann– Whitney U and Kruskal–Wallis tests).