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Median lifespans of dilp1 mutant and dilp1 overexpressing female and male flies exposed to starvation display a sex dimorphism.
| Genotype | Female median lifespan (calculated as % of w1118) | Males | ||
|---|---|---|---|---|
| w1118 | 100 | 100 | 100 | 100 |
| dilp1−/− | 83 (p < 0.001) | 86 (p < 0.001) | 78 (p < 0.001) | 125 (p < 0.001) |
| dilp2−/− | 100 | 100 | 100 | 125 (p < 0.001) |
| dilp1/dilp2−/− | 107 (p < 0.001) | 76 (p < 0.001) | 67 (p < 0.001) | 100 |
| ppl>w1118 | 100 | – | 100 | 100 |
| ppl>dilp1 | 80 (p < 0.001) | – | 90 (p < 0.001) | 100 |
*Data from Post et al. (35).
