Figure 1.

Gray matter associations of altered temporal awareness in the patient cohort. Statistical parametric maps show regional gray matter volume positively associated with the propensity to re-live past events across all syndromic groups (see text and Tables 2, 3 for details). For display purposes, maps have been rendered on coronal sections of the group mean template T1-weighted MR brain image and thresholded at p < 0.001, uncorrected for multiple voxel-wise comparisons over the whole brain volume (areas significant at p_FWE < 0.05 after correction for multiple comparisons within pre-specified neuroanatomical regions of interest are summarized in Table 5); the y-coordinate (mm) in MNI space of the plane of each section is indicated. The color bar codes voxel-wise T scores. The left hemisphere is shown on the left in all sections. The sections traverse the following key structures: (A) anterior middle temporal gyrus/superior temporal sulcus. (B) posterior hippocampus. (C) posterior cingulate cortex. (D) superior parietal lobule.