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. 2020 Apr 21;10:546. doi: 10.3389/fonc.2020.00546

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Copyright © 2020 Pan, Bao and Enders.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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microarray analysis on tumor tissue samples for senescent signature. (A) cDNA-array analysis in the tumor tissues from RAD001 treated mice and control mice showed a slight induction of senescence associated genes (p < 0.05: RAD001 treated group vs. control group). (B) Senescent related genes differentially expressed between control group and RAD001 treated group (p < 0.05) were selected for STRING analysis. Protein-protein interaction was shown.