TABLE 5.

Molecular characteristics of the 34 extended-spectrum cephalosporin- and carbapenem-resistant isolates.

Strain	Pathology	Sequence type	Phylogroup	Phenotype	Beta-lactamase enzyme	Associated resistances	Virulence profiles
A14	UTI	191	A	AmpC	CMY-2	None	fimH
A08	UTI	NT	B2	AmpC	CMY-2	CHL, TET, SUL, TMP, NAL	fimH, iutA, iroN
B03	UTI	4,608	D	AmpC	CMY-2	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, iroN, iss, fuyA
C05	Unknown	12	B2	AmpC	CMY-2	None	fimH, cnf1, focG, papA, hlyD, iroN, ibeA, fuyA
D08	UTI	372	B2	AmpC	CMY-2	None	fimH, focG, ibeA, fuyA
D09	Reproductive tract	1,706	B1	AmpC	CMY-2	None	fimH
E03	UTI	297	B1	AmpC	CMY-2	STR, SUL, TMP	fimH
F06	UTI	4,608	D	AmpC	CMY-2	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	papA, iutA, iss
F10	UTI	12	B2	AmpC	CMY-2	STR, KAN, CHL, SUL, NAL	fimH, cnf1, papA, hlyD, iroN, fuyA
I54	Unknown	141	B2	AmpC	CMY-2	STR, CHL, TET, SUL	fimH, cnf1, papA, hlyD, iroN, fuyA
I58	Otitis	162	B1	AmpC	CMY-2	STR, TET, SUL, NAL, ENR	fim, fuyA
K26	UTI	212	B1	AmpC	CMY-2	None	fimH
N19	Digestive	NT	B2	AmpC	CMY-2	None	focG, fimH, fuyA
Q05	UTI	4,608	D	AmpC	CMY-2	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, iroN, fuyA
Q29	Digestive	1,011	D	AmpC	CMY-2	STR, TET, SUL, TMP, NAL, ENR	fimH, iroN, ibeA
R07	UTI	2,015	B2	AmpC	CMY-2	None	fimH, cnf1, kpsMII, papA, iroN, ibeA, fuyA
T11	UTI	68	D	AmpC	CMY-2	NAL	kpsMII, fimH, fuyA
X25	UTI	372	B2	AmpC	CMY-2	None	fimH, cnf1, focG, papA, sfaS, hlyD, fuyA
Z01	Respiratory	12	B2	AmpC	CMY-2	None	fimH, cnf1, focG, papA, hlyD, iroN, fuyA
T12	Respiratory	1,485	D	Carbapenemase	OXA-48	STR, TET, SUL, TMP	kpsMII, fimH
B04	UTI	410	A	ESBL	CTX-M-153	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, fuyA
B11	UTI	648	D	ESBL	CTX-M-3	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, kpsMII, iutA
C17	UTI	131	B2	ESBL	CTX-M-27	NAL, ENR	fimH, kpsMII, iutA
E08	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	papA, iutA
H20	UTI	90	A	ESBL	CTX-M-27	STR, TET, SUL, TMP, NAL, ENR	fimH
I47	UTI	372	B2	ESBL	CTX-M-15	CHL	kpsMII, iutA, ibeA, fuyA
N01	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, ibeA, fuyA
N11	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, fuyA
N20	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, NAL, ENR	cnf1, papA, hlyD, iutA, fuyA
P24	UTI	23	A	ESBL	CTX-M-1	TET, SUL, TMP	fimH, iutA, iroN, ibeA
T01	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, iroN, fuyA
T03	Reproductive tract	NT	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, kpsMII, papA, hlyD, iutA, iroN, ibeA, fuyA
T13	UTI	648	D	ESBL	CTX-M-15	KAN, TET, NAL, ENR	kpsMII, papA, afa, hlyD, iutA, iroN, ibeA, fuyA
Z09	UTI	410	A	ESBL	CTX-M-15	STR, KAN, GEN, CHL, TET, SUL, TMP, NAL, ENR	fimH, cnf1, papA, hlyD, iutA, fuyA

UTI: urinary tract infection. ¹Antibiotics: STR, streptomycin; KAN, kanamycin; GEN, gentamicin; CHL, chloramphenicol; TET, tetracycline; SUL, sulfonamides; TMP, trimethoprim; NAL, nalidixic acid, ENR, enrofloxacin. ²The A08 isolate is a fumC variant of ST58; N19 is a gyrB variant of ST372; T03 is a purA variant of ST410. ³In bold are all isolates that are chromosomally encoded as shown by Southern blots on I-CeuI PFGE.