TABLE 1.
Genotypic, demographic, and clinical information of all participants.
| SNP ID | Alleles | Location | Call Rate (%) | Test for HWE (P Value) | MAF | |
| GRIN1 | ||||||
| rs11146020 | C/G | upstream 9:137138632 | 100 | 0.6142a | C: 0.195 | |
| GRIA2 | ||||||
| rs3813296 | G/T | Intron 4:157360371 | 100 | 0.1999a | G:0.246 | |
| rs11146020 |
GG = 31 |
CG = 22 |
F value | P value | ||
| rs3813296 | GT = 14 | TT = 17 | GT = 10 | TT = 12 | ||
| Gender | 6M/8F | 8M/9F | 6M/54F | 7M/5F | 1.14 | 0.79b |
| AGE | 26.67 ± 6.08 | 23.87 ± 5.85 | 25.11 ± 7.41 | 25.11 ± 5.04 | 0.47 | 0.71c |
| EDU | 12.42 ± 3.80 | 12.07 ± 2.81 | 12.78 ± 2.68 | 13.56 ± 2.40 | 0.48 | 0.70c |
| Head motion | 0.36 ± 0.21 | 0.44 ± 0.24 | 0.29 ± 0.20 | 0.38 ± 0.19 | 0.51 | 0.63c |
| DUP | 38.42 ± 44.01 | 26.47 ± 16.08 | 24.22 ± 18.44 | 36.89 ± 47.96 | 0.50 | 0.68c |
| SANS | 14.75 ± 11.38 | 14.40 ± 13.14 | 14.00 ± 10.42 | 24.67 ± 13.30 | 1.69 | 0.18c |
| TMT | 46.08 ± 18.83 | 31.07 ± 18.10 | 40.89 ± 16.10 | 52.56 ± 24.98 | 2.63 | 0.06c |
| BACS-SC | 51.75 ± 10.06 | 52.33 ± 13.07 | 47.89 ± 14.22 | 47.56 ± 12.07 | 0.45 | 0.72c |
| HVLT-R | 22.08 ± 5.18 | 24.00 ± 7.00 | 20.56 ± 6.15 | 24.00 ± 4.80 | 0.80 | 0.50c |
| WMS-III SS | 14.58 ± 2.78 | 13.93 ± 4.51 | 13.11 ± 3.44 | 15.11 ± 3.66 | 0.50 | 0.68c |
| NAB-M | 15.00 ± 7.06 | 14.13 ± 5.96 | 11.66 ± 7.90 | 12.22 ± 9.52 | 0.47 | 0.71c |
| BVMT-R | 23.17 ± 7.25 | 25.27 ± 9.19 | 21.89 ± 8.40 | 20.44 ± 9.88 | 0.65 | 0.59c |
| VF | 20.08 ± 6.65 | 18.53 ± 6.00 | 19.33 ± 5.98 | 23.56 ± 7.84 | 1.16 | 0.34c |
| MSCEIT-ME | 86.92 ± 13.19 | 84.93 ± 15.11 | 81.56 ± 15.11 | 96.67 ± 19.98 | 1.58 | 0.21c |
| CPT-IP | 2.42 ± 1.08 | 1.80 ± 1.01 | 2.33 ± 0.87 | 2.22 ± 0.83 | 1.07 | 0.37c |
| Head motion | 0.34 ± 0.07 | 0.29 ± 0.06 | 0.37 ± 0.09 | 0.33 ± 0.08 | 0.70 | 0.55c |
Data are given as mean ± standard deviation; aP value was obtained by hardy-weinberg equilibrium (HWE) test; bP value was obtained by an independence Pearson chi-square test. cThe P and corresponding F values were obtained by a one-way analysis of variance test. MAF, minor allele frequency; EDU, education years; DUP, duration of untreated psychosis; SANS, assessment of negative symptoms; TMT, trail making test; BACS-SC, brief assessment of cognition in schizophrenia-symbol coding; HVLT-R, Hopkins verbal learning test, revised; WMS-III SS, Wechsler memory scale, third edition: spatial span; NAB-M, neuropsychological assessment battery, mazes; BVMT-R, brief visuospatial memory test, revised; VF, verbal fluency; MSCEIT-ME, Mayer-Salovey-Caruso emotional intelligence test, managing emotions; CPT-IP, continuous performance test-identical pairs.