TABLE 3.
Main and interaction effects of rs11146020 and rs3813296 on gray and white matter volumes.
| rs11146020*rs3813296 inteaction effect on gray matter volumes | |||||
| GG/GT vs. GG/TT | |||||
| Brain region | MNI |
T value | P value | ||
| X | Y | Z | |||
| L.Caudate/thalamus | −15 | 14 | 6 | 4.563 | 0.005 |
| R. Caudate/thalamus | 17 | 17 | 6 | 4.288 | 0.005 |
| L.Putamen/caudate | −9 | 13 | −4 | 4.892 | 0.004 |
| R. Putamen/caudate | 16 | 17 | −4 | 5.184 | 0.002 |
|
rs3813296 main effect on white matter volumes | |||||
|
GT vs. TT | |||||
| Brain region |
MNI |
T value | P value | ||
| X | Y | Z | |||
| L. Superior corona radiata | −26 | −3 | 21 | 3.681 | 0.008 |
| R. Superior corona radiata | 26 | −8 | 32 | 3.455 | 0.010 |
|
rs11146020*rs3813296 inteaction effect on white matter volumes | |||||
|
GG/GT vs. CG/TT | |||||
| Brain region |
MNI |
T value | P value | ||
| X | Y | Z | |||
| L. Superior corona radiata | −16 | −6 | 35 | −3.47 | 0.009 |
| R. Superior corona radiata | 29 | −10 | 35 | −3.394 | 0.010 |
P and corresponding T values were obtained by two samples t-test (P < 0.01, FDR correction). X, Y, and Z from MNI (Montreal Neurological Institute) coordinates.