Table 1.
Patient characteristics according to status of perineural invasion.
| Characteristic | JPH cohort: No (%) | AHJU cohort: No (%) | ||||
|---|---|---|---|---|---|---|
| PNI- | PNI+ | P-value | PNI- | PNI+ | P-value | |
| 148 (66.4) | 75 (33.6) | 262 (43.7) | 337 (56.3) | |||
| Age (years) | ||||||
| <65 | 106 (65.4) | 56 (34.6) | 0.630 | 159 (46.0) | 187 (54.0) | 0.201 |
| ≥65 | 42 (68.9) | 19 (31.1) | 103 (40.7) | 150 (59.3) | ||
| Sex | ||||||
| Female | 46 (73.0) | 17 (27.0) | 0.187 | 74 (48.1) | 80 (51.9) | 0.211 |
| Male | 102 (63.8) | 58 (36.3) | 188 (42.2) | 257 (57.8) | ||
| Tumor location | ||||||
| Non-cardia | 96 (66.7) | 48 (33.3) | 0.898 | 141 (52.0) | 130 (48.0) | <0.001 |
| Cardia | 52 (65.8) | 27 (34.2) | 121 (36.9) | 207 (63.1) | ||
| Histology grade | ||||||
| I/II | 73 (64.0) | 41 (36.0) | 0.451 | 168 (49.7) | 170 (50.3) | 0.001 |
| III | 75 (68.8) | 34 (31.2) | 94 (36.0) | 167 (64.0) | ||
| Lymphovascular invasion | ||||||
| Negative | 117 (70.9) | 48 (29.1) | 0.015 | 201 (50.1) | 200 (49.9) | <0.001 |
| Positive | 31 (53.4) | 27 (46.6) | 61 (30.8) | 137 (69.2) | ||
| TNM stage | ||||||
| IB/II | 61 (77.2) | 18 (22.8) | 0.011 | 151 (63.4) | 87 (36.6) | <0.001 |
| III | 87 (60.4) | 57 (39.6) | 111 (30.7) | 250 (69.3) | ||
| Adjuvant chemotherapy | ||||||
| Untreated | 15 (60.0) | 10 (40.0) | 0.474 | 76 (40.0) | 114 (60.0) | 0.209 |
| Treated | 133 (67.2) | 65 (32.8) | 186 (45.5) | 223 (54.5) | ||
JPH, Jiangsu Province Hospital; AHJU, Affiliated Hospital of Jiangsu University.