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. 2020 Apr 12;23(5):101055. doi: 10.1016/j.isci.2020.101055

Table 2.

Biopolymeric Delivery Systems for Encapsulation of Nutraceuticals

Bioactive Compound Category Bioactive Compound Nature-Derived Polymer Used Advantage of Nanoencapsulation Reference
Polyphenols Curcumin Chitosan and gum arabica Improved stability and antioxidant activity of curcumin (Tan et al., 2016)
Curcumin Soluble soya bean polysaccharides Improved the anti-cancer property of curcumin (Pan et al., 2018)
Resveratrol Chitosan/γ-poly (glutamic acid) Improved the solubility and cellular uptake (Jeon et al., 2016)
Resveratrol Zeina Improved bioavailability (Jayan et al., 2019)
Lutein Chitosan/poly-glutamic acid Improved the solubility (Lee and Lee, 2016)
Green tea catechins Zeina Improved cell uptake (Bhushani et al., 2017)
Carotenoids Beta carotene Starcha Intestine specific release of beta carotene (Santoyo-Aleman et al., 2019)
Lutein Starcha Improved solubility and stability of lutein (Fu et al., 2019)
Lycopene Zeina Improved antioxidant activity (Horuz and Belibagli, 2019)
Vitamins Folate B9 Whey protein isolate and resistant starch Improved stability of folic acid (Pérez-Masiá et al., 2015)
Cobalamin B12 Soy protein Improved intestinal transport (Zhang et al., 2015)
Vitamin D Fish oil Improved bioavailability (Walia et al., 2017)
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Considered GRAS by FDA (21 CFR Ch. I [4–1–11 Edition]).