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. 2020 Mar;8(6):349. doi: 10.21037/atm.2020.03.25

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Expression profiles of lncRNAs and mRNAs in NPSLE patients and Non-NPSLE patients. (A,C) Hierarchical clustering of lncRNAs and mRNAs with expression changes greater than two-fold and P value <0.01. NPSLE patient group: NPSLE1-6; Non-NPSLE patient group: Non-NPSLE1-5. Red and green colors represent up- and downregulated genes, respectively; (B,D) Volcano plot of differentially expressed lncRNAs and mRNAs. The horizontal white line represents a P value of 0.01, and vertical white lines represent 2.0-fold changes up and down. X axes are the fold change values (log2 scaled), and Y axes are the P values (log2 scaled). Red and blue plots represent up- and downregulated genes, respectively.